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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AP2A1
All Species:
17.58
Human Site:
S657
Identified Species:
35.15
UniProt:
O95782
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95782
NP_570603.2
977
107546
S657
T
V
S
T
P
S
P
S
A
D
L
L
G
L
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001115458
977
107553
S657
T
V
S
T
P
S
P
S
A
D
L
L
G
L
R
Dog
Lupus familis
XP_541490
922
101289
L637
G
P
A
A
Q
P
S
L
G
P
T
P
E
E
A
Cat
Felis silvestris
Mouse
Mus musculus
P17426
977
107646
S657
T
V
S
T
P
S
P
S
A
D
L
L
G
L
R
Rat
Rattus norvegicus
P18484
938
104026
S656
T
S
A
A
S
T
P
S
P
S
A
D
L
L
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001012914
938
104174
S656
A
S
A
V
S
T
P
S
P
S
A
D
L
L
G
Frog
Xenopus laevis
NP_001089303
939
104392
P657
S
T
S
S
T
P
S
P
S
A
D
L
L
G
L
Zebra Danio
Brachydanio rerio
XP_001922441
959
106027
S657
D
N
S
T
I
A
A
S
N
A
S
T
P
S
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91926
940
105602
N657
N
S
H
S
K
L
N
N
S
N
A
N
T
D
L
Honey Bee
Apis mellifera
XP_394621
937
104937
S657
T
G
A
V
N
N
T
S
A
D
L
L
S
L
S
Nematode Worm
Caenorhab. elegans
NP_509572
925
104161
T656
D
F
D
S
T
N
D
T
T
A
S
L
A
D
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38065
1025
114993
M719
S
R
S
I
M
V
P
M
P
P
P
S
R
R
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.5
91.3
N.A.
98.4
79.4
N.A.
N.A.
79.5
78.3
82.1
N.A.
66.6
68
62.2
N.A.
Protein Similarity:
100
N.A.
99.8
92.7
N.A.
98.8
86.9
N.A.
N.A.
87.4
87
88.1
N.A.
77.8
78.8
74.9
N.A.
P-Site Identity:
100
N.A.
100
0
N.A.
100
26.6
N.A.
N.A.
20
13.3
20
N.A.
0
46.6
6.6
N.A.
P-Site Similarity:
100
N.A.
100
6.6
N.A.
100
40
N.A.
N.A.
33.3
33.3
26.6
N.A.
26.6
60
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
34
17
0
9
9
0
34
25
25
0
9
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
17
0
9
0
0
0
9
0
0
34
9
17
0
17
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
9
9
0
% E
% Phe:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
9
0
0
0
0
0
0
9
0
0
0
25
9
17
% G
% His:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
9
9
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
9
0
9
0
0
34
50
25
50
17
% L
% Met:
0
0
0
0
9
0
0
9
0
0
0
0
0
0
0
% M
% Asn:
9
9
0
0
9
17
9
9
9
9
0
9
0
0
9
% N
% Pro:
0
9
0
0
25
17
50
9
25
17
9
9
9
0
9
% P
% Gln:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
9
0
0
0
0
0
0
0
0
0
0
9
9
25
% R
% Ser:
17
25
50
25
17
25
17
59
17
17
17
9
9
9
9
% S
% Thr:
42
9
0
34
17
17
9
9
9
0
9
9
9
0
0
% T
% Val:
0
25
0
17
0
9
0
0
0
0
0
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _